Description
Product Characteristics:
Aliases: CD 112 antibody, CD112 antibody, CD112 antigen antibody, Herpes virus entry mediator B antibody, Herpes virus entry protein B antibody, Herpesvirus entry mediator B antibody, Herpesvirus entry protein B antibody, Hve B antibody, HveB antibody, Nectin-2 antibody, Nectin2 antibody, Poliovirus receptor like 2 antibody, Poliovirus receptor related 2 (herpesvirus entry mediator B) antibody, Poliovirus receptor related 2 antibody, Poliovirus receptor related protein 2 antibody, Poliovirus receptor-related protein 2 antibody, PRR 2 antibody, PRR2 antibody, PVRL 2 antibody, PVRL2 antibody, PVRL2_HUMAN antibody, PVRR 2 antibody, PVRR2 antibody
Target Information: This gene encodes a single-pass type I membrane glycoprotein with two Ig-like C2-type domains and an Ig-like V-type domain. This protein is one of the plasma membrane components of adherens junctions. It also serves as an entry for certain mutant strains of herpes simplex virus and pseudorabies virus, and it is involved in cell to cell spreading of these viruses. Variations in this gene have been associated with differences in the severity of multiple sclerosis. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]